The World community is currently observing the expanding use of sanctions by states and regional organizations without or beyond authorization of the UN Security Council. Unfortunately, majority of this measures violate international obligations of states and their illegality cannot be excluded via the mechanism of counter-measures. They constitute therefore unilateral coercive measures. The current article is providing an overview of unilateral sanctions currently used by states and regional organizations worldwide, qualifies them from the point of international law, demonstrates impact of unilateral sanctions. Means of their enforcement and over-compliance on the human rights in general, and provides for the detailed analysis of the impact various types of unilateral sanctions to the right to food and food security.