The purpose of this chapter is to consider the effects of unilateral sanctions on regional economic integration treaties, with special reference to the Charter of the Gulf Cooperation Council (GCC) and other treaties concerning economic cooperation among the Gulf countries. There are several regional economic integration and cooperation agreements that have been concluded between states globally. Many of these treaties create regional economic and political organisations to foster close cooperation between the states which are parties to the constituent agreements of such organisations. Examples are the European Union (EU), the North American Free Trade Agreement (NAFTA), the Association of Southeast Asian Nations (ASEAN) and the Gulf Cooperation Council (GCC).